CENTRO is a unique blend of natural ingredients formulated to help restore the proper nutritional balance to the joints by decreasing inflammation and improving joint components function*. Recent scientific research demonstrates that both Osteoarthritis and Rheumatoid arthritis manifest a dysfunction in the maturation and repair of both of the major joint cartilage components: proteoglycans and collagen. CENTRO is a well-rounded alternative health product that addresses all aspects of joint component functions.*
CENTRO joint support contains highly concentrated sesame seed extract known as sesamin, using an innovative enzymes extraction technology, co-patented between CordyBiotech Co., Ltd. and Kasetsart University, Bangkok Thailand, a well-respected university in Agricultural, Science and Argo-industry fields in Thailand.
According to research articles, sesamin has therapeutic benefits for treating inflammation in osteoarthritis as it helps prevent enzymes interleukin-1 (IL-1) from breaking down cartilage and allowing collagen type II production to occur naturally.
Sesamin and sesamolin are lignan compounds found in an extract. They help inhibit enzymes interleukin 1 (IL-1) from mediating bone resorption and cartilage destruction. Sesame seed is also rich in calcium and zinc that boost bone mineral density and bone health.
Centella asiatica (Gotu Kola)'s primary active constituent is triterpenoid compounds: asiaticoside, madecassoside, and madasiatic acid. They promote collagen production, which is a critical component of connective membrane tissues. Also the anti-inflammatory properties of gotu kola may be useful in treating arthritis.
Collagen Type II, derived from chicken sternum cartilage, stimulates cartilage and hyaluronic acid production. It is the primary form of collagen naturally found in joint cartilage that the body needs to rebuild connective tissue. Hyaluronic acid works by acting as a cushion and lubricant in the joints and other tissues as well. Several studies show collagen type II reduces joint pain in rheumatoid arthritis and osteoarthritis.
Soy protein is a plant-based protein that is derived naturally from soy beans. It is high in calcium, protein and isoflavones. Protein is a macronutrient that is essential for the growth and repair of muscle tissue and for the growth and repair of cellular health and function. Calcium and isoflavones promote good bone health.
Cartilage is found throughout the body, most notably covering bone endings in joints such as the knee and hip. A large molecule called aggrecan gives cartilage its unique capacity to bear load and resist compression, and it is this substance that is broken down in arthritis, resulting in weakened cartilage and painful joints.
In healthy joints, cartilage is constantly being broken down, replaced and rebuilt. There is a delicate balance between enzymes called interleukin-1 (IL-1) that break down the cartilage and cells that help restore it. Because of the aging process, disease, or injury, cartilage is being broken down faster than it is being rebuilt. It is believed that osteoarthritis develops due to there being more enzymes destroying the cartilage than chondrocytes (cartilage forming cells) creating it. When this process continues over a period of time cartilage begins to erode. This results in increased knee joint pain, deformity, and limited joint mobility.
CENTRO Joint support formula promotes cartilage and hyaluronic acid production and protects cartilage from damaged by enzyme IL-1.* A well-rounded joint support you should try.